免疫原
Synthesized peptide derived from human Chimaerin 2. AA range:1-130
特异性
This antibody detects endogenous levels of Chimaerin 2 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors.
基因名称(Gene Name)
CHN2 ARHGAP3 BCH
蛋白名称
Beta-chimaerin (Beta-chimerin) (Rho GTPase-activating protein 3)
其他名称
=_xlfn.TEXTJOIN(";",TRUE,W3192,X3192,Y3192,Z3192)
细胞定位
Membrane ; Peripheral membrane protein .
组织表达
Highest levels in the brain and pancreas. Also expressed in the heart , placenta , and weakly in the kidney and liver. Expression is much reduced in the malignant gliomas , compared to normal brain or low-grade astrocytomas.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)