免疫原
Synthesized peptide derived from human COPG2. AA range:407-477
特异性
This antibody detects endogenous levels of COPG2 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles , which further mediate biosynthetic protein transport from the ER , via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes , and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals , the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs) , which are small GTP-binding proteins; the complex also influences the Golgi structural integrity , as well as the processing , activity , and endocytic recycling of LDL receptors (By similarity) .
蛋白名称
Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP)
其他名称
=_xlfn.TEXTJOIN(";",TRUE,W3186,X3186,Y3186,Z3186)
细胞定位
Cytoplasm , cytosol . Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasmic vesicle , COPI-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi , as well as on the vesicles/buds originating from it. Tends to be more abundant in the trans-Golgi network compared to the cis-Golgi. .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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