免疫原
Synthesized peptide derived from human PIH1D1. AA range:1-43
特异性
This antibody detects endogenous levels of PIH1D1 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles . Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription . Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 . Positively regulates the assembly and activity of the mTORC1 complex .
基因名称(Gene Name)
PIH1D1 NOP17
蛋白名称
PIH1 domain-containing protein 1 (Nucleolar protein 17 homolog)
其他名称
=_xlfn.TEXTJOIN(";",TRUE,W3174,X3174,Y3174,Z3174)
组织表达
Expressed at low levels in normal mammary epithelial cells (at protein level) (PubMed:24036451) . Highest expression in lung , leukocyte and placenta. Expressed at lower levels in brain , prostate , colon , heart , small intestine , liver , ovary , pancreas , skeletal muscle , spleen , testis and thymus (PubMed:21078300) .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)