免疫原
Synthesized peptide derived from human SMPDL3B. AA range:122-222
特异性
This antibody detects endogenous levels of SMPDL3B at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Lipid-modulating phosphodiesterase . Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling (By similarity) . Has in vitro phosphodiesterase activity , but the physiological substrate is unknown . Lacks activity with phosphocholine-containing lipids , but can cleave CDP-choline , and can release phosphate from ATP and ADP (in vitro) (By similarity) .
基因名称（Gene Name）
SMPDL3B ASML3B
蛋白名称
Acid sphingomyelinase-like phosphodiesterase 3b (ASM-like phosphodiesterase 3b) (EC 3.1.4.-)
其他名称
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细胞定位
Secreted . Cell membrane ; Lipid-anchor , GPI-anchor .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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