免疫原
Synthesized peptide derived from human CPNE6. AA range:160-260
特异性
This antibody detects endogenous levels of CPNE6 at Human, Mouse
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Binds phospholipid membranes in a calcium-dependent manner (By similarity) . Plays a role in dendrite formation by melanocytes .
蛋白名称
Copine-6 (Copine VI) (Neuronal-copine) (N-copine)
其他名称
=_xlfn.TEXTJOIN(";",TRUE,W3137,X3137,Y3137,Z3137)
细胞定位
Cytoplasm . Cell membrane . Endosome . Cytoplasmic vesicle , clathrin-coated vesicle . Perikaryon . Cell projection , dendrite . Mainly cytoplasmic in absence of calcium. Associated predominantly with membranes in presence of calcium. Translocates to the cell membrane in a calcium-dependent manner. Colocalized with transferrin in intracellular clathrin-coated membrane vesicles in a calcium-dependent manner. .
组织表达
Widely expressed in the brain (PubMed:9645480 , PubMed:10403379 , PubMed:12949241) . Expressed weakly in the kidney , liver and fetal heart (PubMed:12949241) . Expressed in melanocytes (PubMed:23999003) .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)