免疫原
Synthesized peptide derived from human ARHGAP29. AA range:806-906
特异性
This antibody detects endogenous levels of ARHGAP29 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA , and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1 , suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.
基因名称(Gene Name)
ARHGAP29 PARG1
蛋白名称
Rho GTPase-activating protein 29 (PTPL1-associated RhoGAP protein 1) (Rho-type GTPase-activating protein 29)
其他名称
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组织表达
Widely expressed. Highly expressed in skeletal muscle and heart. Expressed at intermediate level in placenta , liver and pancreas. Weakly expressed in brain , lung and kidney.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)