免疫原
Synthesized peptide derived from human PLVAP. AA range:226-326
特异性
This antibody detects endogenous levels of PLVAP at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability , endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development.
基因名称（Gene Name）
PLVAP FELS PV1
蛋白名称
Plasmalemma vesicle-associated protein (Fenestrated endothelial-linked structure protein) (Plasmalemma vesicle protein 1) (PV-1)
其他名称
PLVAP FELS PV1;Plasmalemma vesicle-associated protein (Fenestrated endothelial-linked structure protein) (Plasmalemma vesicle protein 1) (PV-1)
细胞定位
Cell membrane ; Single-pass type II membrane protein . Membrane , caveola ; Single-pass type II membrane protein . Cytoplasm , perinuclear region . Membrane-associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels. Also colocalized with CAV1 in perinuclear region. .
组织表达
Expressed in lung , kidney , heart , aorta , placenta , muscle , pituitary gland , adrenals , mammary gland , bladder , lymph node , bone marrow , trachea , digestive tract , liver and tumor-associated endothelium.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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