免疫原
Synthesized peptide derived from human TIP30. AA range:1-68
特异性
This antibody detects endogenous levels of TIP30 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Oxidoreductase required for tumor suppression. NADPH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
基因名称（Gene Name）
HTATIP2 CC3 TIP30
蛋白名称
Oxidoreductase HTATIP2 (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2)
其他名称
HTATIP2 CC3 TIP30;Oxidoreductase HTATIP2 (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2)
细胞定位
Cytoplasm . Nucleus envelope .
组织表达
Ubiquitous. Highest level in liver. High levels in lung , skeletal muscle , pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain. Not expressed or low levels in variant small cell lung carcinomas , 33% of hepatocellular carcinomas and neuroblastomas.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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