免疫原
Synthesized peptide derived from human SRGAP3. AA range:59-129
特异性
This antibody detects endogenous levels of SRGAP3 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
GTPase-activating protein for RAC1 and perhaps Cdc42 , but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons.
基因名称(Gene Name)
SRGAP3 ARHGAP14 KIAA0411 KIAA1156 MEGAP SRGAP2
蛋白名称
SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)
其他名称
SRGAP3 ARHGAP14 KIAA0411 KIAA1156 MEGAP SRGAP2;SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)
组织表达
Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)