免疫原
Synthesized peptide derived from human DIS3L. AA range:618-688
特异性
This antibody detects endogenous levels of DIS3L at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
基因名称（Gene Name）
DIS3L DIS3L1 KIAA1955
蛋白名称
DIS3-like exonuclease 1 (EC 3.1.13.-)
其他名称
DIS3L DIS3L1 KIAA1955;DIS3-like exonuclease 1 (EC 3.1.13.-)
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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