免疫原
Synthesized peptide derived from human IL-17RE
特异性
This antibody detects endogenous levels of IL-17RE at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.
基因名称（Gene Name）
IL17RE UNQ3056/PRO9877
蛋白名称
Interleukin-17 receptor E (IL-17 receptor E) (IL-17RE)
其他名称
IL 17 receptor E;IL 17RE;IL17RE;IL-17RE;interleukin 17 receptor E;IL17RE UNQ3056/PRO9877;Interleukin-17 receptor E (IL-17 receptor E) (IL-17RE)
细胞定位
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Cytoplasm .; [Isoform 3]: Secreted .; [Isoform 4]: Cytoplasm .; [Isoform 5]: Secreted .
组织表达
Predominantly expressed in mucosal tissues with high levels in keratinocytes and colon epithelial cells. Very low expression in dermal fibroblasts. Expressed in various tumor cell lines.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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