免疫原
Synthesized peptide derived from human ZBTB1
特异性
This antibody detects endogenous levels of ZBTB1 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Acts as a transcriptional repressor . Represses cAMP-responsive element (CRE)-mediated transcriptional activation . In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis . Plays a key role in the transcriptional regulation of T lymphocyte development (By similarity).
基因名称（Gene Name）
ZBTB1 KIAA0997
蛋白名称
Zinc finger and BTB domain-containing protein 1
其他名称
KIAA997;ZBTB1;ZBTB1 KIAA0997;Zinc finger and BTB domain-containing protein 1
细胞定位
Nucleus . Nucleus, nucleoplasm . Localized in dot-like structures in the nucleus (PubMed:21706167). Colocalized with SMRT in nuclear bodies (PubMed:20797634). The sumoylated form is preferentially located in the nucleoplasm outside the nuclear bodies(PubMed:20797634). .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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