免疫原
Synthesized peptide derived from human MLXIP
特异性
This antibody detects endogenous levels of MLXIP at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
基因名称(Gene Name)
MLXIP BHLHE36 KIAA0867 MIR MONDOA
蛋白名称
MLX-interacting protein (Class E basic helix-loop-helix protein 36) (bHLHe36) (Transcriptional activator MondoA)
其他名称
BHLHE36;Class E basic helix-loop-helix protein 36;KIAA0867;MIR;MLX interacting protein;MLXIP BHLHE36 KIAA0867 MIR MONDOA;MLX-interacting protein (Class E basic helix-loop-helix protein 36) (bHLHe36) (Transcriptional activator MondoA)
细胞定位
Cytoplasm . Nucleus . Mitochondrion outer membrane . Predominantly cytoplasmic but shuttles between cytoplasm and nucleus when associated with MLX. Also associates with the outer mitochondrial membrane and may shuttle between the outer mitochondrial membrane and the nucleus. .
组织表达
Widely expressed in adult tissues. Most abundant in skeletal muscle.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)