免疫原
Synthesized peptide derived from human TID1
特异性
This antibody detects endogenous levels of TID1 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.
基因名称（Gene Name）
DNAJA3 HCA57 TID1
蛋白名称
DnaJ homolog subfamily A member 3;mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog)
其他名称
DnaJ protein Tid 1;DNAJA3;HCA57;hTid 1;TID 1;TID1;DNAJA3 HCA57 TID1;DnaJ homolog subfamily A member 3;mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog)
细胞定位
Mitochondrion matrix. Cytoplasm, cytosol . Cell junction, synapse, postsynaptic cell membrane ; Peripheral membrane protein . Recruited to the postsynaptic cell membrane of the neuromuscular junction through interaction with MUSK. .
组织表达
Widely expressed with highest levels in heart, liver, lung and skeletal muscles. Also expressed in keratinocytes.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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