免疫原
Synthesized peptide derived from human DNAJC10
特异性
This antibody detects endogenous levels of DNAJC10 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.
基因名称（Gene Name）
DNAJC10 ERDJ5 UNQ495/PRO1012
蛋白名称
DnaJ homolog subfamily C member 10 (ER-resident protein ERdj5) (Macrothioredoxin) (MTHr)
其他名称
JPDI;MTHr;ERdj5;PDIA19;DNAJC10;DNAJC10 ERDJ5 UNQ495/PRO1012;DnaJ homolog subfamily C member 10 (ER-resident protein ERdj5) (Macrothioredoxin) (MTHr)
细胞定位
Endoplasmic reticulum lumen .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
联系我们
关注我们
您当前的位置： 
成功添加到购物车
