免疫原
Synthesized peptide derived from human NMT1
特异性
This antibody detects endogenous levels of NMT1 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins . Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3' . Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle .
蛋白名称
Glycylpeptide N-tetradecanoyltransferase 1 (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1)
其他名称
EC:2.3.1.-;EC:2.3.1.97;Glycylpeptide N-tetradecanoyltransferase 1;HsNMT1;Myristoyl-CoA:protein N-myristoyltransferase 1;NMT1 NMT;Glycylpeptide N-tetradecanoyltransferase 1 (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1)
细胞定位
Cytoplasm . Cytoplasm, cytosol . Membrane ; Peripheral membrane protein . Copurifies with ribosomes. .
组织表达
Heart, gut, kidney, liver and placenta.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)