免疫原
Synthesized peptide derived from human ARPC4
特异性
This antibody detects endogenous levels of ARPC4 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) . The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility . In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA . The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) .
基因名称（Gene Name）
ARPC4 ARC20
蛋白名称
Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC)
其他名称
ARC20;Arp2/3 complex 20 kDa subunit;ARPC4;p20 Arc;ARPC4 ARC20;Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC)
细胞定位
Cytoplasm, cytoskeleton . Cell projection . Nucleus .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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