免疫原
Synthesized peptide derived from human IRF2BP1
特异性
This antibody detects endogenous levels of IRF2BP1 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.
蛋白名称
Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 6.3.2.-)
其他名称
EC:2.3.2.27;Interferon regulatory factor 2-binding protein 1;IRF 2 binding protein 1;IRF 2BP1;IRF-2-binding protein 1;IRF2BP1;Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 6.3.2.-)
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)