免疫原
Synthesized peptide derived from human DNAJC6/AUXILIN
特异性
This antibody detects endogenous levels of DNAJC6/AUXILIN at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles. Plays a role in clathrin-mediated endocytosis in neurons (By similarity).
基因名称(Gene Name)
DNAJC6 KIAA0473
蛋白名称
Putative tyrosine-protein phosphatase auxilin (DnaJ homolog subfamily C member 6)
其他名称
Auxilin;DNAJC6;DJC6;EC:3.1.3.-;KIAA0473;DNAJC6 KIAA0473;Putative tyrosine-protein phosphatase auxilin (DnaJ homolog subfamily C member 6)
细胞定位
Expressed in various brain regions, including cerebellum, corpus callosum, cortex, striatum, brainstem, pons, putamen, spinal cord and substantia nigra. Very low expression in non-neural tissues such as leukocytes, liver, adipose tissue, skeletal muscle and bone marrow.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)