免疫原
Synthesized peptide derived from human MIOS
特异性
This antibody detects endogenous levels of MIOS at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex . It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 .
蛋白名称
WD repeat-containing protein mio
其他名称
MIO;Sea4;Yulink;MIOS;WD repeat-containing protein mio
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)