免疫原
Synthesized peptide derived from human PHACTR1
特异性
This antibody detects endogenous levels of PHACTR1 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity . Involved in the regulation of cortical neuron migration and dendrite arborization (By similarity).
基因名称(Gene Name)
PHACTR1 KIAA1733 RPEL1
蛋白名称
Phosphatase and actin regulator 1
其他名称
RPEL;DEE70;RPEL1;EIEE70;dJ257A7.2;PHACTR1;PHACTR1 KIAA1733 RPEL1;Phosphatase and actin regulator 1
细胞定位
Cytoplasm . Cell junction, synapse . Nucleus . Enriched at synapses (By similarity). Cytoplasmic in resting cells, and is imported into the nucleus upon serum stimulation. Interaction with actin prevents nuclear import (By similarity). .
组织表达
Detected in umbilical vein endothelial cells.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)