免疫原
Synthesized peptide derived from human KDM1B
特异性
This antibody detects endogenous levels of KDM1B at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.
基因名称（Gene Name）
KDM1B AOF1 C6orf193 LSD2
蛋白名称
Lysine-specific histone demethylase 1B (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2)
其他名称
AOF1;LSD2;C6orf193;1E1A3;KDM1B AOF1 C6orf193 LSD2;Lysine-specific histone demethylase 1B (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2)
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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