免疫原
Synthesized peptide derived from human PDZD8
特异性
This antibody detects endogenous levels of PDZD8 at Human
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Molecular tethering protein that connects endoplasmic reticulum and mitochondria membranes . PDZD8-dependent endoplasmic reticulum-mitochondria membrane tethering is essential for endoplasmic reticulum-mitochondria Ca(2+) transfer . In neurons, involved in the regulation of dendritic Ca(2+) dynamics by regulating mitochondrial Ca(2+) uptake in neurons . Plays an indirect role in the regulation of cell morphology and cytoskeletal organization . May inhibit herpes simplex virus 1 infection at an early stage .
基因名称（Gene Name）
PDZD8 PDZK8
蛋白名称
PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR-104)
其他名称
LYVAC;PDZ domain containing 8;PDZ domain-containing protein 8;PDZK8;Sarcoma antigen NY-SAR-84/NY-SAR-104;PDZD8 PDZK8;PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR-104)
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein . Localizes at mitochondria-endoplasmic reticulum contact sites. .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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