免疫原
Synthesized peptide derived from human SORBS1
特异性
This antibody detects endogenous levels of SORBS1 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).
基因名称（Gene Name）
SORBS1 KIAA0894 KIAA1296 SH3D5
蛋白名称
Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
其他名称
CAP;c-Cbl-associated protein;SH3D5;SORB1;Sorbin and SH3 domain-containing protein 1;SORBS1 KIAA0894 KIAA1296 SH3D5;Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
细胞定位
Cell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus . Nucleus matrix . Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation. .
组织表达
Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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