免疫原
Synthesized peptide derived from human HSD17B7
特异性
This antibody detects endogenous levels of HSD17B7 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Bifunctional enzyme involved in steroid-hormone metabolism and cholesterol biosynthesis . Catalyzes the NADP(H)-dependent reduction of estrogens and androgens and regulates the biological potency of these steroids. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2) . Converts dihydrotestosterone (DHT) to its inactive form 5a-androstane-3b,17b-diol . Converts moderately progesterone to 3beta-hydroxypregn-4-ene-20-one, leading to its inactivation . Additionally, participates in the post-squalene cholesterol biosynthesis, as a 3-ketosteroid reductase . ; [Isoform 3]: Does not have enzymatic activities toward E1 and DHT.
基因名称（Gene Name）
HSD17B7 UNQ2563/PRO6243
蛋白名称
3-keto-steroid reductase (17-beta-hydroxysteroid dehydrogenase 7) (17-beta-HSD 7) (Estradiol 17-beta-dehydrogenase 7) (EC 1.1.1.62)
其他名称
PRAP;SDR37C1;HSD17B7;HSD17B7 UNQ2563/PRO6243;3-keto-steroid reductase (17-beta-hydroxysteroid dehydrogenase 7) (17-beta-HSD 7) (Estradiol 17-beta-dehydrogenase 7) (EC 1.1.1.62)
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein .
组织表达
Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. ; [Isoform 3]: Expressed in eye ciliary epithelial cells and neuroendocrine cells.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
联系我们
关注我们
您当前的位置： 
成功添加到购物车
