免疫原
Synthesized peptide derived from human BPI
特异性
This antibody detects endogenous levels of BPI at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
蛋白名称
Bactericidal permeability-increasing protein (BPI) (CAP 57)
其他名称
rBPI;BPIFD1;BPI;Bactericidal permeability-increasing protein (BPI) (CAP 57)
细胞定位
Secreted . Cytoplasmic granule membrane . Membrane-associated in polymorphonuclear Leukocytes (PMN) granules. .
组织表达
Restricted to cells of the myeloid series.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)