免疫原
Synthesized peptide derived from human ZnT7
特异性
This antibody detects endogenous levels of ZnT7 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity).
基因名称(Gene Name)
SLC30A7 ZNT7 ZNTL2
蛋白名称
Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) (Znt-like transporter 2)
其他名称
18159J1Rik;26134N15Rik;4833428C12Rik;AI467242;DKFZp686M368;SLC3A7;Solute carrier family 3 (zinc transporter);member 7;Solute carrier family 3 member 7;Zinc transporter 7;ZnT-7;Znt-like transporter 2;ZNT7;ZNT7_HUMAN;ZNTL2;SLC30A7 ZNT7 ZNTL2;Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) (Znt-like transporter 2)
细胞定位
Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)