免疫原
Synthesized peptide derived from human PREB
特异性
This antibody detects endogenous levels of PREB at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER. ; Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.
基因名称（Gene Name）
PREB SEC12
蛋白名称
Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12)
其他名称
SEC12;PREB;PREB SEC12;Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12)
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein . Nucleus . Concentrates at endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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