免疫原
Synthesized peptide derived from human CPNE3
特异性
This antibody detects endogenous levels of CPNE3 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation .
基因名称（Gene Name）
CPNE3 CPN3 KIAA0636
蛋白名称
Copine-3 (Copine III)
其他名称
CPN3;PRO1071;CPNE3;CPNE3 CPN3 KIAA0636;Copine-3 (Copine III)
细胞定位
Nucleus . Cytoplasm . Cell membrane . Cell junction . Cell junction, focal adhesion . Associates to the membrane in a calcium-dependent manner (PubMed:20010870). Translocates to the cell membrane and the nucleus in a calcium- or growth factor heregulin-dependent manner (PubMed:21087455, PubMed:20010870). Colocalizes with the tyrosine phosphorylated ERBB2 form at cell membrane and focal adhesions in a calcium- or growth factor heregulin-dependent manner (PubMed:20010870). .
组织表达
Expressed in breast and weakly in prostate and ovarian tissues (PubMed:20010870). Expressed in neutrophils (at protein level) (PubMed:12949241). Widely expressed (PubMed:11041869). Expressed in the brain. Expressed in neutrophil precursors from the bone marrow and peripheral blood (PubMed:12949241). Expressed in primary breast tumors and ovarian endometrioid adenocarcinoma (PubMed:20010870).
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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