免疫原
Synthesized peptide derived from human TRPM6
特异性
This antibody detects endogenous levels of TRPM6 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region.
基因名称(Gene Name)
TRPM6 CHAK2
蛋白名称
Transient receptor potential cation channel subfamily M member 6 (Channel kinase 2) (Melastatin-related TRP cation channel 6)
其他名称
CHAK2;Channel kinase 2;HMGX;HOMG;HOMG1;HSH;TRPM6;TRPM6 CHAK2;Transient receptor potential cation channel subfamily M member 6 (Channel kinase 2) (Melastatin-related TRP cation channel 6)
细胞定位
Cell membrane ; Multi-pass membrane protein.
组织表达
Highly expressed in kidney and colon. Isoform TRPM6a and isoform TRPM6b, are coexpressed with TRPM7 in kidney, and testis, and are also found in several cell lines of lung origin. Isoform TRPM6c is detected only in testis and in NCI-H510A small cell lung carcinoma cells.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)