免疫原
Synthesized peptide derived from human HERP
特异性
This antibody detects endogenous levels of HERP at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins . Could enhance presenilin-mediated amyloid-beta protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway .
基因名称（Gene Name）
HERPUD1 HERP KIAA0025 MIF1
蛋白名称
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (Methyl methanesulfonate (MMF)-inducible fragment protein 1)
其他名称
HERP;HERP1_HUMAN;HERPUD1;Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 1;Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 1 protein;Homocysteine responsive endoplasmic reticulum resident ubiquitin like domain member 1;Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein;KIAA25;Methyl methanesulfonate (MMF) inducible fragment protein 1;Methyl methanesulfonate (MMF)-inducible fragment protein 1;MIF1;MMS inducible;SUP;HERPUD1 HERP KIAA0025 MIF1;Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (Methyl methanesulfonate (MMF)-inducible fragment protein 1)
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
组织表达
Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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