免疫原
Synthesized peptide derived from human SPC24
特异性
This antibody detects endogenous levels of SPC24 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity . Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore . The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules .
基因名称（Gene Name）
SPC24 SPBC24
蛋白名称
Kinetochore protein Spc24 (hSpc24)
其他名称
SPBC24;SPC24;SPC24 SPBC24;Kinetochore protein Spc24 (hSpc24)
细胞定位
Nucleus . Chromosome, centromere, kinetochore . Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore. .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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