免疫原
Synthesized peptide derived from human VASH2
特异性
This antibody detects endogenous levels of VASH2 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function . Critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning . Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis . Plays a role in axon formation .
基因名称（Gene Name）
VASH2 VASHL
蛋白名称
Vasohibin-2 (Vasohibin-like protein)
其他名称
Vasohibin-like protein;Vasohibin-2;VASHL;Tubulinyl-Tyr carboxypeptidase 2;EC:3.4.17.17;VASH2 VASHL;Vasohibin-2 (Vasohibin-like protein)
细胞定位
Cytoplasm . Secreted . Cytoplasm, cytoskeleton . Mainly localizes in the cytoplasm (PubMed:19204325). Some fraction is secreted via a non-canonical secretion system; interaction with SVBP promotes secretion (PubMed:20736312). Associates with microtubules (PubMed:31235911). .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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