免疫原
Synthesized peptide derived from human TMEM97
特异性
This antibody detects endogenous levels of TMEM97 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cancer cells . Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation . Under investigation for its potential diagnostic and therapeutic uses . May play a role as a regulator of cellular cholesterol homeostasis . May function as sterol isomerase . May alter the activity of some cytochrome P450 proteins .
基因名称（Gene Name）
TMEM97 MAC30
蛋白名称
Transmembrane protein 97 (Protein MAC30)
其他名称
MAC3;Protein MAC3;S2R;Sigma2 receptor;Sigma-2 receptor;TMEM97 MAC30;Transmembrane protein 97 (Protein MAC30)
细胞定位
Nucleus membrane ; Multi-pass membrane protein . Rough endoplasmic reticulum membrane ; Multi-pass membrane protein . Localized at cell membrane and in lysosomes in sterol-depleted cells when expression of endogenous TMEM97 is stimulated. .
组织表达
Widely expressed in normal tissues. Expressed in pancreatic, renal, breast, colon, ovarian surface epithelial (OSE) cells. Highly expressed in various proliferating cancer cells
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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