免疫原
Synthesized peptide derived from human SEC6
特异性
This antibody detects endogenous levels of SEC6 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
基因名称(Gene Name)
EXOC3 SEC6 SEC6L1
蛋白名称
Exocyst complex component 3 (Exocyst complex component Sec6)
其他名称
EXOC 3;Exoc3;EXOC3_HUMAN;Exocyst complex component 3;Exocyst complex component Sec 6;Exocyst complex component Sec6;rSec 6;Sec 6;Sec 6 homolog;Sec 6p;Sec6;SEC6 L1;SEC6 like 1;Sec6 protein;SEC6L1;Sec6p;EXOC3 SEC6 SEC6L1;Exocyst complex component 3 (Exocyst complex component Sec6)
细胞定位
Cytoplasm . Cytoplasm, perinuclear region . Cell projection, growth cone . Midbody . Golgi apparatus . Cell projection, neuron projection . Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB-dependent (PubMed:18756269). .
组织表达
Expressed in epididymis (at protein level).
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)