免疫原
Synthesized peptide derived from human Galectin 10
特异性
This antibody detects endogenous levels of Galectin 10 at Human
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).
蛋白名称
Eosinophil lysophospholipase (Charcot-Leyden crystal protein) (CLC) (Galectin-10) (Gal-10) (Lysolecithin acylhydrolase)
其他名称
CLC;Charcot Leyden crystal protein;Charcot-Leyden crystal protein;Gal 10;Gal-10;Eosinophil lysophospholipase (Charcot-Leyden crystal protein) (CLC) (Galectin-10) (Gal-10) (Lysolecithin acylhydrolase)
细胞定位
Cytoplasm, cytosol . Cytoplasmic granule . Localized in granules from where it may be secreted or transported to other locations in the cell.
组织表达
Expressed abundantly in the bone marrow. Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils. Expressed in CD25-positive regulatory T-cells (Treg) (at protein level). Found in intestinal tissue from patients with Celiac disease, expression is directly related to the histological grade of mucosal damage and to the number of eosinophils found in the duodenal lesion (at protein level). Found in sputum of patients with eosinophilic inflammatory diseases such as asthma (at protein level).
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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