免疫原
Synthesized peptide derived from human PRKCDBP
特异性
This antibody detects endogenous levels of PRKCDBP at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Regulates the traffic and/or budding of caveolae . Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (By similarity).
基因名称(Gene Name)
PRKCDBP SRBC
蛋白名称
Protein kinase C delta-binding protein (Cavin-3) (Serum deprivation response factor-related gene product that binds to C-kinase) (hSRBC)
其他名称
SRBC;HSRBC;PRKCDBP;cavin-3;PRKCDBP SRBC;Protein kinase C delta-binding protein (Cavin-3) (Serum deprivation response factor-related gene product that binds to C-kinase) (hSRBC)
细胞定位
Cytoplasm . Membrane, caveola . Cytoplasm, cytosol . Localizes in the caveolae in a caveolin-dependent manner. .
组织表达
Skeletal muscle, liver, stomach, lung, kidney and heart (at protein level). Strongly expressed in mammary and epithelial cells.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)