免疫原
Synthesized peptide derived from human N6AMT1
特异性
This antibody detects endogenous levels of N6AMT1 at Human
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Methyltransferase that can methylate proteins and, to a lower extent, arsenic . Catalytic subunit of a heterodimer with TRMT112, which monomethylates 'Lys-12' of histone H4 (H4K12me1), a modification present at the promoters of numerous genes encoding cell cycle regulators . Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5-methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif . Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated . May also play a role in the modulation of arsenic-induced toxicity by mediating the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid . It however only plays a limited role in arsenic metabolism compared with AS3MT .
基因名称（Gene Name）
N6AMT1 C21orf127 HEMK2 PRED28
蛋白名称
HemK methyltransferase family member 2 (M.HsaHemK2P) (N(6)-adenine-specific DNA methyltransferase 1)
其他名称
C21orf127;EC:2.1.1.-;HemK methyltransferase family member 2;HEMK2;KMT9;N6AMT1 C21orf127 HEMK2 PRED28;HemK methyltransferase family member 2 (M.HsaHemK2P) (N(6)-adenine-specific DNA methyltransferase 1)
组织表达
Widely expressed, with highest expression in parathyroid and pituitary glands, followed by adrenal gland and kidney, and lowest expression in leukocytes and mammary gland.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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