免疫原
Synthesized peptide derived from human MAGT1
特异性
This antibody detects endogenous levels of MAGT1 at Human,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Accessory component of the STT3B-containing form of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains . Involved in N-glycosylation of STT3B-dependent substrates . Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. ; May be involved in Mg(2+) transport in epithelial cells.
基因名称(Gene Name)
MAGT1 IAG2 PSEC0084 UNQ628/PRO1244
蛋白名称
Magnesium transporter protein 1 (MagT1) (Implantation-associated protein) (IAP)
其他名称
IAP;XMEN;MRX95;OST3B;CDG1CC;PRO0756;SLC58A1;bA217H1.1;MAGT1;MAGT1 IAG2 PSEC0084 UNQ628/PRO1244;Magnesium transporter protein 1 (MagT1) (Implantation-associated protein) (IAP)
细胞定位
Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum . Endoplasmic reticulum membrane ; Multi-pass membrane protein .
组织表达
Ubiquitous. Expressed at very low levels in brain, lung and kidney.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)