免疫原
Synthesized peptide derived from human TXNDC4
特异性
This antibody detects endogenous levels of TXNDC4 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum.
基因名称(Gene Name)
ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075
蛋白名称
Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)
其他名称
PDIA10;TXNDC4;ERP44;ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075;Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)
细胞定位
Endoplasmic reticulum lumen .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)