免疫原
Synthesized peptide derived from human KIF3A
特异性
This antibody detects endogenous levels of KIF3A at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole.
基因名称(Gene Name)
KIF3A KIF3
蛋白名称
Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A)
其他名称
FLA10;KLP-20;KIF3A;KIF3A KIF3;Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A)
细胞定位
Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localizes to the subdistal appendage region of the centriole. .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)