免疫原
Synthesized peptide derived from human PRICKLE1
特异性
This antibody detects endogenous levels of PRICKLE1 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.
基因名称（Gene Name）
PRICKLE1 RILP
蛋白名称
Prickle-like protein 1 (REST/NRSF-interacting LIM domain protein 1)
其他名称
EPM1B;Prickle-like protein 1;REST/NRSF-interacting LIM domain protein 1;RILP;PRICKLE1 RILP;Prickle-like protein 1 (REST/NRSF-interacting LIM domain protein 1)
细胞定位
Nucleus membrane . Cytoplasm, cytosol . A smaller amount is detected in the cytosol.
组织表达
Expressed at highest levels in placenta and at lower levels in lung, liver, kidney and pancreas. Expressed in thalamus, hippocampus, cerebral cortex, and cerebellum (in neurons rather than glia).
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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