免疫原
Synthesized peptide derived from human TBC1D17
特异性
This antibody detects endogenous levels of TBC1D17 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known.
蛋白名称
TBC1 domain family member 17
其他名称
TBC1 domain family member 17;TBC1 domain family;member 17;TBC1D17
细胞定位
Cytoplasmic vesicle, autophagosome .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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