免疫原
Synthesized peptide derived from human ANK3
特异性
This antibody detects endogenous levels of ANK3 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption . ; [Isoform 5]: May be part of a Golgi-specific membrane cytoskeleton in association with beta-spectrin.
蛋白名称
Ankyrin-3 (ANK-3) (Ankyrin-G)
其他名称
MRT37;ANKYRIN-G;ANK3;Ankyrin-3 (ANK-3) (Ankyrin-G)
细胞定位
Cytoplasm, cytoskeleton . Cell projection, axon . Cell membrane, sarcolemma . Cell junction, synapse, postsynaptic cell membrane . Lysosome . Cell membrane, sarcolemma, T-tubule . In skeletal muscle, localized at costameres and neuromuscular junctions. In macrophages, associated with lysosomes. .; [Isoform 5]: Cytoplasm, cytoskeleton . Golgi apparatus .
组织表达
Expressed in brain, neurons, muscles and other tissues.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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