免疫原
Synthesized peptide derived from human Calsequestrin 2
特异性
This antibody detects endogenous levels of Calsequestrin 2 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
蛋白名称
Calsequestrin-2 (Calsequestrin;cardiac muscle isoform)
其他名称
Calsequestrin 2;CASQ2;PDIB2;Calsequestrin-2 (Calsequestrin;cardiac muscle isoform)
细胞定位
Sarcoplasmic reticulum lumen . This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of cardiac and slow skeletal muscle cells. .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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