免疫原
Synthesized peptide derived from human PDLIM7
特异性
This antibody detects endogenous levels of PDLIM7 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity).
基因名称(Gene Name)
PDLIM7 ENIGMA
蛋白名称
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
其他名称
1113B1Rik;Enigma;LIM domain protein;LIM domain protein enigma;LIM mineralization protein 1;Lim mineralization protein 3;LIM mineralization protein;LMP 1;LMP;LMP1;LMP3;PDLI7_HUMAN;PDLIM 7;Pdlim7;PDZ and LIM doamin protein 7;PDZ and LIM domain 7;PDZ and LIM domain protein 7;Protein enigma;PDLIM7 ENIGMA;PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity). .
组织表达
Isoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)