免疫原
Synthesized peptide derived from human CRAT
特异性
This antibody detects endogenous levels of CRAT at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation . Responsible for the synthesis of short- and branched-chain acylcarnitines . Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates . Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates .
基因名称(Gene Name)
CRAT CAT1
蛋白名称
Carnitine O-acetyltransferase (Carnitine acetylase) (Carnitine acetyltransferase) (CAT) (CrAT)
其他名称
CAT;CAT1;NBIA8;CRAT;CRAT CAT1;Carnitine O-acetyltransferase (Carnitine acetylase) (Carnitine acetyltransferase) (CAT) (CrAT)
细胞定位
Endoplasmic reticulum . Peroxisome . Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .; [Isoform 1]: Mitochondrion .; [Isoform 2]: Peroxisome .
组织表达
Mostly in skeletal muscle, less in heart, liver and pancreas, only weakly detectable in brain, placenta, lung and kidney.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)