免疫原
Synthesized peptide derived from human AP3D1
特异性
This antibody detects endogenous levels of AP3D1 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation . In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity).
基因名称(Gene Name)
AP3D1 PRO0039
蛋白名称
AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin)
其他名称
ADTD;HPS10;hBLVR;AP3D1;AP3D1 PRO0039;AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin)
细胞定位
Cytoplasm . Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side .
组织表达
Present in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)