免疫原
Synthesized peptide derived from human KIF2A
特异性
This antibody detects endogenous levels of KIF2A at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity.
基因名称(Gene Name)
KIF2A KIF2 KNS2
蛋白名称
Kinesin-like protein KIF2A (Kinesin-2) (hK2)
其他名称
HK2;KIF2;CDCBM3;KIF2A;KIF2A KIF2 KNS2;Kinesin-like protein KIF2A (Kinesin-2) (hK2)
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)