免疫原
Synthesized peptide derived from human ASTN2
特异性
This antibody detects endogenous levels of ASTN2 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6).
基因名称（Gene Name）
ASTN2 KIAA0634
其他名称
HNAC1;BCDase;LCDase;NCDase;N-CDase;ASAH2;ASTN2 KIAA0634;Astrotactin-2
细胞定位
Membrane ; Multi-pass membrane protein . Perikaryon . Cytoplasm, cell cortex . Early endosome . Late endosome . Cytoplasmic vesicle, clathrin-coated vesicle . Cytoplasmic vesicle . Integral membrane protein not detected at the cell membrane. Detected in cytoplasmic vesicles in the cell cortex, close to the anterior pole of migrating neurons. Detected at the base of the leading process in migrating neurons. .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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